What is the Clinical Significance of Oligoclonal Bands?
The presence of OCBs is often associated with various neurological conditions, particularly those involving inflammation and autoimmune responses. They are most commonly linked to multiple sclerosis (MS), where their presence in the CSF but not in the serum is a diagnostic criterion. OCBs can also be found in other conditions such as neuromyelitis optica, Lupus, Lyme disease, and viral infections like HIV and syphilis.
