What Are the Challenges and Risks Associated with Complement Inhibitors?
While complement inhibitors offer promising therapeutic benefits, they also come with certain challenges and risks:
1. Infection Risk: Since the complement system plays a crucial role in immune defense, inhibiting it can increase the risk of infections, particularly from encapsulated bacteria like Neisseria meningitidis. 2. Cost: Complement inhibitors can be extremely expensive, limiting their accessibility. 3. Long-term Safety: The long-term safety profile of these drugs is still under investigation, and there may be unforeseen adverse effects with prolonged use.
