What are the Challenges in Gene Therapy for Neurology?
Several challenges need to be addressed for effective gene therapy in neurology: 1. Delivery to the Brain: The Blood-Brain Barrier (BBB) is a significant hurdle for delivering therapeutic agents to the brain. 2. Immune Response: The body’s immune system may react against the introduced vectors or genes. 3. Long-term Expression: Ensuring that the therapeutic gene remains active for a sufficient duration to have a meaningful impact.
