Is AQP4 Involved in Other Neurological Conditions?
Yes, beyond NMO, AQP4 is also being studied in the context of cerebral edema, brain tumors, and epilepsy. In cerebral edema, altered expression of AQP4 can lead to detrimental fluid accumulation. In brain tumors, AQP4 expression levels can influence tumor growth and spread. In epilepsy, abnormal AQP4 function can affect the extracellular ionic balance, potentially contributing to seizure activity.
